ros production — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8869	B355252		Others
	B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.		Others
T1633	β-Carotene	Carotaben,Beta-Carotene,Provitamin A	Apoptosis , ROS , Endogenous Metabolite
	β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene...		Apoptosis , ROS , Endogenous Metabolite
T72082	Compound T72082(SC)		ROS
	ROS-IN-1 is a mitochondrial ROS inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ROS) production.		ROS
T77574	ROS inducer 1		ROS , Antibiotic
	ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actini...		ROS , Antibiotic
T33296	Merodantoin		Apoptosis
	Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin targets cancer cells expressing KRAS mutations involved in Akt-dependent ROS production.		Apoptosis
T38423	CL097	CL097	Reactive Oxygen Species , TLR
	CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production.		Reactive Oxygen Species , TLR
T24865	Tenivastatin	L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid	ROS , HMG-CoA Reductase
	Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia.		ROS , HMG-CoA Reductase
T21275	Azoxystrobin	HSDB 7017,ICI-A 5504,Bankit,ICIA-5504,Amistar	Antifungal
	Azoxystrobin (Bankit) is a broad-spectrum fungicide. Azoxystrobin induces ROS production, cell apoptosis and mitochondrial respiration by blocking electron transfer between cytochromes b and c1.		Antifungal
T4168	Visomitin	SKQ1	Reactive Oxygen Species
	Visomitin (SKQ1) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).		Reactive Oxygen Species
T0129	Sanguinarine chloride	Pseudochelerythrine chloride,Sanguinarium chloride	Apoptosis , EGFR , VEGFR , Antibacterial , Parasite , Autophagy
	Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS).
TQ0298	Fagomine	D-Fagomine	ROS , glycosidase
	Fagomine (D-Fagomine) is a mild glycosidase inhibitor, an analog of 1-deoxynojirimycin (DNJ) with hypoglycemic activity, and Fagomine reduces intracellular reactive oxygen species (ROS) production and malondialdehyde (MD...		ROS , glycosidase
T15433	GSK2795039		Apoptosis , Reactive Oxygen Species , ROS , NADPH
	GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).		Apoptosis , Reactive Oxygen Species , ROS , NADPH
T10668	Camalexin		Reactive Oxygen Species , ROS , Antibacterial , Antifungal
	Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.		Reactive Oxygen Species , ROS , Antibacterial , Antifungal
T36488	LYG-202	LYG202,LYG 202	Apoptosis , ROS
	LYG-202 is a novel flavonoid with piperazine substitution and antitumor effects in vivo and in vitro.LYG-202 induced apoptosis in MCF-7, MDA-MB-231, and MDA-MB-435 cells, and increased intracellular ROS production.		Apoptosis , ROS
T78554	Tyrosinase-IN-12		Tyrosinase
	Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25 µM. Tyrosinase-IN-12 has significant antioxidant and free r...		Tyrosinase
T75636	(E/Z)-Squalene	(E/Z)-Super Squalene,(E/Z)-AddaVax
	(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production and induces apoptosis and necrosis in a concentration and time-dependent manner. (E/Z)-Squalene accumulates in the liver an...
T11139	(E/Z)-BCI	NSC 150117	Apoptosis , Phosphatase
	(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signa...		Apoptosis , Phosphatase
T36902	RA375	RA375	Proteasome
	RA375, an inhibitor of RPN13 (26S proteasome regulatory subunit), enhances UPR signaling, ROS production, and apoptosis. Demonstrating ten times the efficacy against cancer lines compared to RA190, RA375 owes its increas...		Proteasome
T3834	8-Epideoxyloganic acid		ROS , Immunology/Inflammation related
	8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl...		ROS , Immunology/Inflammation related
T5S2283	Sesamolin		p38 MAPK , Caspase , JNK
	1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...		p38 MAPK , Caspase , JNK